Neurohormones and Heart Failure

Neurohormones are a collection of several chemical messengers of cardiac and extracardiac origin which are found in high circulating levels in adults with Chronic heart failure (CHF). Neurohormonal systems are normally stimulated under conditions of acute volume depletion, activated by the low cardiac output and arterial pressure. However, sustained and chronic activation of these systems can cause progressive ventricular remodelling and worsening heart failure, as occurs in congestive heart failure (CHF).

  • Pathophysiology of chronic heart failure (CHF)
  • Congenital heart disease
  • Angiotensin-Converting Enzyme inhibitor therapy

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