Cardiovascular genetics is the study of the genetic mechanisms of circulatory functioning and pathophysiology. The risk of heart disease often occurs in families, suggesting a genetic influence. These can be single gene defects or many genes that together increase the risk of heart disease. Heritable factors underlie a number of cardiovascular diseases including diseases of the heart’s muscle, electric circuit, and vasculature. These congenital heart conditions sometimes referred to as cardiovascular genetic disorders, may go undiagnosed for years before being recognized or causing symptoms. Hypertrophic cardiomyopathy (MCH) is the most frequent hereditary cardiovascular disease.