The study of the genetic mechanisms of circulatory functioning and pathophysiology is known as Cardiovascular Genetics. The risk of heart disease often occurs in families, suggesting a genetic influence. These can be single gene defects or may include multiple genes that together increase the risk of heart disease. a number of cardiovascular diseases including diseases of the heart’s muscle, electric circuit and vasculature involve heritable factors. These congenital heart conditions, also sometimes referred to as cardiovascular genetic disorders, may go undiagnosed for years before being recognized or showing symptoms. Hypertrophic cardiomyopathy (MCH) is the most frequent hereditary cardiovascular disease.